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Neuroinflammatory signals drive spinal curve formation in zebrafish models of idiopathic scoliosis

The etiopathogenesis of idiopathic scoliosis (IS), a highly prevalent spinal deformity that occurs in the absence of obvious congenital or physiological abnormalities, is poorly understood. Although recent zebrafish genetic studies have linked cilia motility and cerebrospinal fluid (CSF) flow defect...

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Detalles Bibliográficos
Publicado en:Sci Adv
Autores principales: Van Gennip, J. L. M., Boswell, C. W., Ciruna, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291318/
https://ncbi.nlm.nih.gov/pubmed/30547092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav1781
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