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ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

Scoliosis is a complex genetic disorder of the musculoskeletal system, characterized by three-dimensional rotation of the spine. Curvatures caused by malformed vertebrae (congenital scoliosis (CS)) are apparent at birth. Spinal curvatures with no underlying vertebral abnormality (idiopathic scoliosi...

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Detalhes bibliográficos
Main Authors: Hayes, Madeline, Gao, Xiaochong, Yu, Lisa X, Paria, Nandina, Henkelman, R. Mark, Wise, Carol A., Ciruna, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155517/
https://ncbi.nlm.nih.gov/pubmed/25182715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5777
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