Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

Ym1 and RELMα are established effector molecules closely synonymous with Th2-type inflammation and associated pathology. Here, we show that whilst largely dependent on IL-4Rα signaling during a type 2 response, Ym1 and RELMα also have IL-4Rα-independent expression patterns in the lung. Notably, we f...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Sutherland, Tara E., Rückerl, Dominik, Logan, Nicola, Duncan, Sheelagh, Wynn, Thomas A., Allen, Judith E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291165/
https://ncbi.nlm.nih.gov/pubmed/30500858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007423
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