The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics

Alternatively activated macrophages (AAMφ) are a major component of the response to helminth infection; however, their functions remain poorly defined. To better understand the helminth-induced AAMφ phenotype, we performed a systems-level analysis of in vivo derived AAMφ using an established mouse m...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Thomas, Graham D., Rückerl, Dominik, Maskrey, Benjamin H., Whitfield, Phillip D., Blaxter, Mark L., Allen, Judith E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314526/
https://ncbi.nlm.nih.gov/pubmed/23074280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-442640
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