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Altered binding of tumor antigenic peptides to MHC class I affects CD8(+) T cell-effector responses

T-cell priming occurs when a naïve T cell recognizes cognate peptide-MHC complexes on an activated antigen presenting cell. The circumstances of this initial priming have ramifications on the fate of the newly primed T cell. Newly primed CD8(+) T cells can embark onto different trajectories, with so...

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Udgivet i:Cancer Immunol Res
Main Authors: Clancy-Thompson, Eleanor, Devlin, Christine A., Tyler, Paul M., Servos, Mariah M., Ali, Lestat R., Ventre, Katherine S., Bhuiyan, M. Aladdin, Bruck, Patrick T., Birnbaum, Michael E., Dougan, Stephanie K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290996/
https://ncbi.nlm.nih.gov/pubmed/30352798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0348
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