Clinical impact of measurable residual disease monitoring by ultradeep next generation sequencing in NPM1 mutated acute myeloid leukemia

Detection of measurable residual disease (MRD) by mutation specific techniques has prognostic relevance in NPM1 mutated AML (NPM1(mut) AML). However, the clinical utility of next generation sequencing (NGS) to detect MRD in AML remains unproven. We analysed the clinical significance of monitoring MR...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Patkar, Nikhil, Kodgule, Rohan, Kakirde, Chinmayee, Raval, Goutham, Bhanshe, Prasanna, Joshi, Swapnali, Chaudhary, Shruti, Badrinath, Y., Ghoghale, Sitaram, Kadechkar, Shraddha, Khizer, Syed Hasan, Kannan, Sadhana, Shetty, Dhanalaxmi, Gokarn, Anant, Punatkar, Sachin, Jain, Hasmukh, Bagal, Bhausaheb, Menon, Hari, Sengar, Manju, Khattry, Navin, Tembhare, Prashant, Subramanian, Papagudi, Gujral, Sumeet
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290958/
https://ncbi.nlm.nih.gov/pubmed/30564301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26400
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