Clinical impact of panel-based error-corrected next generation sequencing versus flow cytometry to detect measurable residual disease (MRD) in acute myeloid leukemia (AML)

We accrued 201 patients of adult AML treated with conventional therapy, in morphological remission, and evaluated MRD using sensitive error-corrected next generation sequencing (NGS-MRD) and multiparameter flow cytometry (FCM-MRD) at the end of induction (PI) and consolidation (PC). Nearly 71% of pa...

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Publicado no:Leukemia
Main Authors: Patkar, Nikhil, Kakirde, Chinmayee, Shaikh, Anam Fatima, Salve, Rakhi, Bhanshe, Prasanna, Chatterjee, Gaurav, Rajpal, Sweta, Joshi, Swapnali, Chaudhary, Shruti, Kodgule, Rohan, Ghoghale, Sitaram, Deshpande, Nilesh, Shetty, Dhanalaxmi, Khizer, Syed Hasan, Jain, Hasmukh, Bagal, Bhausaheb, Menon, Hari, Khattry, Navin, Sengar, Manju, Tembhare, Prashant, Subramanian, Papagudi, Gujral, Sumeet
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102181/
https://ncbi.nlm.nih.gov/pubmed/33558666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-021-01131-6
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