Clinical impact of measurable residual disease monitoring by ultradeep next generation sequencing in NPM1 mutated acute myeloid leukemia

Detection of measurable residual disease (MRD) by mutation specific techniques has prognostic relevance in NPM1 mutated AML (NPM1(mut) AML). However, the clinical utility of next generation sequencing (NGS) to detect MRD in AML remains unproven. We analysed the clinical significance of monitoring MR...

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Pubblicato in:Oncotarget
Autori principali: Patkar, Nikhil, Kodgule, Rohan, Kakirde, Chinmayee, Raval, Goutham, Bhanshe, Prasanna, Joshi, Swapnali, Chaudhary, Shruti, Badrinath, Y., Ghoghale, Sitaram, Kadechkar, Shraddha, Khizer, Syed Hasan, Kannan, Sadhana, Shetty, Dhanalaxmi, Gokarn, Anant, Punatkar, Sachin, Jain, Hasmukh, Bagal, Bhausaheb, Menon, Hari, Sengar, Manju, Khattry, Navin, Tembhare, Prashant, Subramanian, Papagudi, Gujral, Sumeet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290958/
https://ncbi.nlm.nih.gov/pubmed/30564301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26400
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