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Genetic insights into the morass of metastatic heterogeneity

Tumour heterogeneity poses a substantial problem for the clinical management of cancer. Somatic evolution of the cancer genome results in genetically distinct subclones in the primary tumour with different biological properties and therapeutic sensitivities. The problem of heterogeneity is compounde...

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Bibliografski detalji
Izdano u:Nat Rev Cancer
Glavni autori: Hunter, Kent W., Amin, Ruhul, Deasy, Sarah, Ha, Ngoc-Han, Wakefield, Lalage
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290469/
https://ncbi.nlm.nih.gov/pubmed/29422598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.126
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