Intratumoral genetic heterogeneity in metastatic melanoma is accompanied by variation in malignant behaviors

BACKGROUND: Intratumoral heterogeneity is a major obstacle for the treatment of cancer, as the presence of even minor populations that are insensitive to therapy can lead to disease relapse. Increased clonal diversity has been correlated with a poor prognosis for cancer patients, and we therefore ex...

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Bibliografiske detaljer
Main Authors: Anaka, Matthew, Hudson, Christopher, Lo, Pu-Han, Do, Hongdo, Caballero, Otavia L, Davis, Ian D, Dobrovic, Alexander, Cebon, Jonathan, Behren, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852494/
https://ncbi.nlm.nih.gov/pubmed/24119551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-40
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