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CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response as compared to established cell lines

PURPOSE: CD133(+) glioblastoma (GB) tumor stem-like cells (TSCs) have been defined as radioresistant. However, whereas previously classified relative to CD133(−) cells, the radiosensitivity of CD133+ TSCs with respect to the standard GB model, established glioma cell lines, has not been determined....

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: McCord, Amy M., Jamal, Muhammad, Williams, Eli S., Camphausen, Kevin, Tofilon, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290462/
https://ncbi.nlm.nih.gov/pubmed/19671863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0263
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