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Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization

Toward developing a model system for investigating the role of the microenvironment in the radioresistance of glioblastoma (GBM), human glioblastoma stem-like cells (GSCs) were grown in coculture with human astrocytes. Using a trans-well assay, survival analyses showed that astrocytes significantly...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Rath, Barbara H, Wahba, Amy, Camphausen, Kevin, Tofilon, Philip J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673998/
https://ncbi.nlm.nih.gov/pubmed/26518290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.510
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