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Translation initiation factor eIF4E is a target for tumor cell radiosensitization

A core component in the cellular response to radiation occurs at the level of translational control of gene expression. Because a critical element in translation control is the availability of the initiation factor eIF4E, which selectively enhances the cap-dependent translation of mRNAs, we investig...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Hayman, Thomas J., Williams, Eli S., Jamal, Muhammad, Shankavaram, Uma T., Camphausen, Kevin, Tofilon, Philip J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327305/
https://ncbi.nlm.nih.gov/pubmed/22397984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0329
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