Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase

Macrophages exposed to the Th2 cytokines interleukin (IL) IL-4 and IL-13 exhibit a distinct transcriptional response, commonly referred to as M2 polarization. Recently, IL-4-induced polarization of murine bone marrow-derived macrophages (BMDMs) has been linked to acetyl-CoA levels through the activi...

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Udgivet i:Front Immunol
Main Authors: Namgaladze, Dmitry, Zukunft, Sven, Schnütgen, Frank, Kurrle, Nina, Fleming, Ingrid, Fuhrmann, Dominik, Brüne, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290342/
https://ncbi.nlm.nih.gov/pubmed/30568658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02858
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