GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells

GATA2 deficiency is an inherited or sporadic genetic disorder characterized by distinct cellular deficiency, bone marrow failure, various infections, lymphedema, pulmonary alveolar proteinosis, and predisposition to myeloid malignancies resulting from heterozygous loss-of-function mutations in the G...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Jung, Moonjung, Cordes, Stefan, Zou, Jizhong, Yu, Shiqin J., Guitart, Xavi, Hong, So Gun, Dang, Vinh, Kang, Elaine, Donaires, Flavia S., Hassan, Sergio A., Albitar, Maher, Hsu, Amy P., Holland, Steven M., Hickstein, Dennis D., Townsley, Danielle, Dunbar, Cynthia E., Winkler, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2018
Sujets:
Hematopoiesis and Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290105/
https://ncbi.nlm.nih.gov/pubmed/30538114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018017137
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