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Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering
The combination of epigenetic reprogramming with advanced genome editing technologies opened a new avenue to study disease mechanisms, particularly of disorders with depleted target tissue. Bone marrow failure syndromes (BMFS) typically present with a marked reduction of peripheral blood cells due t...
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| Publicado en: | Mol Ther |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700116/ https://ncbi.nlm.nih.gov/pubmed/26435409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.180 |
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