GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells

GATA2 deficiency is an inherited or sporadic genetic disorder characterized by distinct cellular deficiency, bone marrow failure, various infections, lymphedema, pulmonary alveolar proteinosis, and predisposition to myeloid malignancies resulting from heterozygous loss-of-function mutations in the G...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Jung, Moonjung, Cordes, Stefan, Zou, Jizhong, Yu, Shiqin J., Guitart, Xavi, Hong, So Gun, Dang, Vinh, Kang, Elaine, Donaires, Flavia S., Hassan, Sergio A., Albitar, Maher, Hsu, Amy P., Holland, Steven M., Hickstein, Dennis D., Townsley, Danielle, Dunbar, Cynthia E., Winkler, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290105/
https://ncbi.nlm.nih.gov/pubmed/30538114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018017137
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