PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation

The genetic aberrations that drive mixed phenotype acute leukemia (MPAL) remain largely unknown, with the exception of a small subset of MPALs harboring BCR-ABL1 and MLL translocations. We performed clinicopathologic and genetic evaluation of 52 presumptive MPAL cases at Memorial Sloan Kettering Can...

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Bibliografiset tiedot
Julkaisussa:Blood Adv
Päätekijät: Xiao, Wenbin, Bharadwaj, Maheetha, Levine, Max, Farnhoud, Noushin, Pastore, Friederike, Getta, Bartlomiej M., Hultquist, Anne, Famulare, Christopher, Medina, Juan S., Patel, Minal A., Gao, Qi, Lewis, Natasha, Pichardo, Janine, Baik, Jeeyeon, Shaffer, Brian, Giralt, Sergio, Rampal, Raajit, Devlin, Sean, Cimera, Robert, Zhang, Yanming, E. Arcila, Maria, Papaemmanuil, Elli, Levine, Ross L., Roshal, Mikhail
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2018
Aiheet:
Myeloid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290101/
https://ncbi.nlm.nih.gov/pubmed/30530780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018023531
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