PHF6 and DNMT3A mutations are enriched in distinct subgroups of mixed phenotype acute leukemia with T-lineage differentiation

The genetic aberrations that drive mixed phenotype acute leukemia (MPAL) remain largely unknown, with the exception of a small subset of MPALs harboring BCR-ABL1 and MLL translocations. We performed clinicopathologic and genetic evaluation of 52 presumptive MPAL cases at Memorial Sloan Kettering Can...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Xiao, Wenbin, Bharadwaj, Maheetha, Levine, Max, Farnhoud, Noushin, Pastore, Friederike, Getta, Bartlomiej M., Hultquist, Anne, Famulare, Christopher, Medina, Juan S., Patel, Minal A., Gao, Qi, Lewis, Natasha, Pichardo, Janine, Baik, Jeeyeon, Shaffer, Brian, Giralt, Sergio, Rampal, Raajit, Devlin, Sean, Cimera, Robert, Zhang, Yanming, E. Arcila, Maria, Papaemmanuil, Elli, Levine, Ross L., Roshal, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290101/
https://ncbi.nlm.nih.gov/pubmed/30530780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018023531
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