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Endogenous IL-10 Maintains Immune Tolerance but IL-10 Gene Transfer Exacerbates Autoimmune Cholangitis
The immunomodulatory effect of IL-10 as an immunosuppressive and anti-inflammatory cytokine is well known. Taking advantage of our established mouse model of autoimmune cholangitis using 2-octynoic acid conjugated ovalbumin (2-OA-OVA) induction, we compared liver pathology, immune cell populations a...
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| Vydáno v: | J Autoimmun |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289859/ https://ncbi.nlm.nih.gov/pubmed/30274824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.09.009 |
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