Targeted Codelivery of Doxorubicin and IL-36γ Expression Plasmid for An Optimal Chemo-Gene Combination Therapy against Cancer Lung Metastasis

Cancer metastasis is the main cause for the high mortality in breast cancer patients. In this work we developed a polymer POEG-st-Pmor for targeted co-delivery of IL-36γ expression plasmid and doxorubicin (Dox) to lung metastasis of breast cancer. The polymer readily formed micelles that were effect...

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Udgivet i:Nanomedicine
Main Authors: Chen, Yichao, Sun, Jingjing, Huang, Yixian, Liu, Yanhua, Liang, Lei, Yang, Da, Lu, Binfeng, Li, Song
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289619/
https://ncbi.nlm.nih.gov/pubmed/30308300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.09.005
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