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Probing Translocation in Mutants of the Anthrax Channel: Atomically Detailed Simulations with Milestoning
Anthrax toxin consists of a cation channel and two protein factors. Translocation of the anthrax protein factors from endosomal to the cytosolic compartment is a complex process that utilizes the cation channel. An atomically detailed understanding of the function of the anthrax translocation machin...
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| Veröffentlicht in: | J Phys Chem B |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289263/ https://ncbi.nlm.nih.gov/pubmed/30338689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b08304 |
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