Načítá se...

The Impact of Protonation on Early Translocation of Anthrax Lethal Factor: Kinetics From Molecular Dynamics Simulations and Milestoning Theory

We report atomically detailed molecular dynamics simulations of the permeation of the lethal factor (LF) N-terminal segment through the anthrax channel. The N-terminal chain is unstructured and leads the permeation process for the LF protein. The simulations are conducted in explicit solvent with Mi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Ma, Piao, Cardenas, Alfredo E., Chaudhari, Mangesh I., Elber, Ron, Rempe, Susan B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656527/
https://ncbi.nlm.nih.gov/pubmed/29019235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07419
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!