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CellSpecks: A Software for Automated Detection and Analysis of Calcium Channels in Live Cells

To couple the fidelity of patch-clamp recording with a more high-throughput screening capability, we pioneered a, to our knowledge, novel approach to single-channel recording that we named “optical patch clamp.” By using highly sensitive fluorescent Ca(2+) indicator dyes in conjunction with total in...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Shah, Syed Islamuddin, Smith, Martin, Swaminathan, Divya, Parker, Ian, Ullah, Ghanim, Demuro, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289074/
https://ncbi.nlm.nih.gov/pubmed/30447989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.10.015
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