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The Probability of Triggering Calcium Puffs Is Linearly Related to the Number of Inositol Trisphosphate Receptors in a Cluster

Puffs are local Ca(2+) signals that arise by Ca(2+) liberation from the endoplasmic reticulum through concerted opening of tightly clustered inositol trisphosphate receptor/channels (IP(3)R). They serve both local signaling functions and trigger global Ca(2+) waves. The numbers of functional IP(3)R...

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Autors principals: Dickinson, George D., Swaminathan, Divya, Parker, Ian
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328715/
https://ncbi.nlm.nih.gov/pubmed/22768938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.029
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