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Ca(2+) puffs originate from pre-established stable clusters of inositol trisphosphate receptors
Intracellular Ca(2+) signaling crucially depends upon the clustered organization of inositol trisphosphate receptors (IP(3)Rs) in the ER membrane that liberate Ca(2+) to generate local signals known as Ca(2+) puffs. Clusters of IP(3)Rs have been proposed to assemble rapidly in response to IP(3) itse...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897231/ https://ncbi.nlm.nih.gov/pubmed/19934435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000466 |
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