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5-hydroxymethylcytosine in E-Box motifs ACAT∣GTG and ACAC∣GTG increases DNA-binding of the B-HLH transcription factor TCF4.
We evaluated DNA binding of the B-HLH family members TCF4 and USF1 using protein binding microarrays (PBMs) containing double-stranded DNA probes with cytosine on both strands or 5-methylcytosine (5mC) or 5-hydroxymethylcytosine (5hmC) on one DNA strand and cytosine on the second strand. TCF4 prefer...
Shranjeno v:
| izdano v: | Integr Biol (Camb) |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289052/ https://ncbi.nlm.nih.gov/pubmed/27485769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00079g |
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