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Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain

One carbon metabolism is regulated by the availability of nutrients known as methyl donors, and disruption of this pathway can affect multiple physiological systems. DNA methylation, critical for the regulation of gene expression, is linked to one carbon metabolism, and can be altered by perinatal d...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: McKee, SE, Zhang, S, Chen, L, Rabinowitz, JD, Reyes, TM
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288810/
https://ncbi.nlm.nih.gov/pubmed/29423909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14319
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