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Methyl Donor Supplementation Blocks the Adverse Effects of Maternal High Fat Diet on Offspring Physiology

Maternal consumption of a high fat diet during pregnancy increases the offspring risk for obesity. Using a mouse model, we have previously shown that maternal consumption of a high fat (60%) diet leads to global and gene specific decreases in DNA methylation in the brain of the offspring. The presen...

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Detalhes bibliográficos
Main Authors: Carlin, JesseLea, George, Robert, Reyes, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642194/
https://ncbi.nlm.nih.gov/pubmed/23658839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063549
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