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Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain

One carbon metabolism is regulated by the availability of nutrients known as methyl donors, and disruption of this pathway can affect multiple physiological systems. DNA methylation, critical for the regulation of gene expression, is linked to one carbon metabolism, and can be altered by perinatal d...

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Detalles Bibliográficos
Publicado en:J Neurochem
Autores principales: McKee, SE, Zhang, S, Chen, L, Rabinowitz, JD, Reyes, TM
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288810/
https://ncbi.nlm.nih.gov/pubmed/29423909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14319
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