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Dasatinib sensitises triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells

BACKGROUND: Patients with triple negative breast cancer (TNBC) exhibit poor prognosis and are at high risk of tumour relapse, due to the resistance to chemotherapy. These aggressive phenotypes are in part attributed to the presence of breast cancer stem cells (BCSCs). Therefore, targeting BCSCs is a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Tian, Jun, Raffa, Fatmah Al, Dai, Meiou, Moamer, Alaa, Khadang, Baharak, Hachim, Ibrahim Y., Bakdounes, Khldoun, Ali, Suhad, Jean-Claude, Bertrand, Lebrun, Jean-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288167/
https://ncbi.nlm.nih.gov/pubmed/30482914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0287-3
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