Dasatinib + Gefitinib, a non platinum-based combination with enhanced growth inhibitory, anti-migratory and anti-invasive potency against human ovarian cancer cells

Por Thibault, Benoît, Jean-Claude, Bertrand
Publicado no J Ovarian Res (2017)

A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cel...

Por Senhaji Mouhri, Zhor, Goodfellow, Elliot, Jean-Claude, Bertrand
Publicado no BMC Cancer (2017)

The Concept of Divergent Targeting through the Activation and Inhibition of Receptors as a Novel Chemotherapeutic Strategy: Signaling Responses to Strong DNA-Reactive Combinatorial...

Por Watt, Heather L., Rachid, Zakaria, Jean-Claude, Bertrand J.
Publicado em 2012

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O(6)-methylguanine-DNA methyltransferase with a double arm hybrid molecule

Por Rupp, Martin, Mouhri, Zhor Senhaji, Williams, Christopher, Jean-Claude, Bertrand J.
Publicado no Oncotarget (2018)

Sensitivity to PRIMA-1(MET) is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

Por Patyka, Mariia, Sharifi, Zeinab, Petrecca, Kevin, Mansure, Jose, Jean-Claude, Bertrand, Sabri, Siham
Publicado no Oncotarget (2016)

Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities

Por Daniel, Paul, Sabri, Siham, Chaddad, Ahmad, Meehan, Brian, Jean-Claude, Bertrand, Rak, Janusz, Abdulkarim, Bassam S.
Publicado no Front Oncol (2019)

(15)N-, (13)C- and (1)H-NMR Spectroscopy Characterization and Growth Inhibitory Potency of a Combi-Molecule Synthesized by Acetylation of an Unstable Monoalkyltriazene

Por Senhaji Mouhri, Zhor, Goodfellow, Elliot, Kelley, Steven P., Stein, Robin S., Rogers, Robin D., J. Jean-Claude, Bertrand
Publicado no Molecules (2017)

Radiomics in Glioblastoma: Current Status and Challenges Facing Clinical Implementation

Por Chaddad, Ahmad, Kucharczyk, Michael Jonathan, Daniel, Paul, Sabri, Siham, Jean-Claude, Bertrand J., Niazi, Tamim, Abdulkarim, Bassam
Publicado no Front Oncol (2019)

Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC...

Por Elsayed, Shadia A., El-Hendawy, Ahmed M., Mostafa, Sahar I., Jean-Claude, Bertrand J., Todorova, Margarita, Butler, Ian S.
Publicado em 2010

Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting

Por Rao, Suman, Larroque-Lombard, Anne-Laure, Peyrard, Lisa, Thauvin, Cédric, Rachid, Zakaria, Williams, Christopher, Jean-Claude, Bertrand J.
Publicado no PLoS One (2015)

Pilot study investigating the prognostic significance of thymidine phosphorylase expression in patients with metastatic breast cancer: a single institution retrospective analysis

Por Tedeschi, Anna Lisa, Eslami, Zohreh, Garoufalis, Evgenia, Saleh, Ramy R, Omeroglu, Atilla, Altinel, Gulbeyaz, Ait-Tihyaty, Maria, Jean-Claude, Bertrand, Mihalcioiu, Catalin
Publicado no Onco Targets Ther (2015)

Dasatinib sensitises triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells

Por Tian, Jun, Raffa, Fatmah Al, Dai, Meiou, Moamer, Alaa, Khadang, Baharak, Hachim, Ibrahim Y., Bakdounes, Khldoun, Ali, Suhad, Jean-Claude, Bertrand, Lebrun, Jean-Jacques
Publicado no Br J Cancer (2018)