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Dichloroacetate and Salinomycin Exert a Synergistic Cytotoxic Effect in Colorectal Cancer Cell Lines

In the present study, we examined a hypothesis that dichloroacetate, a metabolic inhibitor, might efficiently potentiate the cytotoxic effect of salinomycin, an antibiotic ionophore, on two human colorectal cancer derived cell lines DLD-1 and HCT116. First, we performed a series of dose response exp...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Skeberdytė, Aistė, Sarapinienė, Ieva, Aleksander-Krasko, Jan, Stankevičius, Vaidotas, Sužiedėlis, Kęstutis, Jarmalaitė, Sonata
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288092/
https://ncbi.nlm.nih.gov/pubmed/30531808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35815-4
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