Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation

Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs in mitosis. Here, we show that two highly cons...

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Publicat a:eLife
Autors principals: Pellacani, Claudia, Bucciarelli, Elisabetta, Renda, Fioranna, Hayward, Daniel, Palena, Antonella, Chen, Jack, Bonaccorsi, Silvia, Wakefield, James G, Gatti, Maurizio, Somma, Maria Patrizia
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287947/
https://ncbi.nlm.nih.gov/pubmed/30475206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40325
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