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The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure
INT6/eIF3e is a highly conserved component of the translation initiation complex that interacts with both the 26S proteasome and the COP9 signalosome, two complexes implicated in ubiquitin-mediated protein degradation. The INT6 gene was originally identified as the insertion site of the mouse mammar...
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| Udgivet i: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448806/ https://ncbi.nlm.nih.gov/pubmed/28505193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006784 |
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