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Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity
Mitochondrial quality control is an essential process required to maintain cellular homeostasis and functions. Mutations of PINK1 and PRKN/PARK2 contribute to the risk of Parkinson disease. Our recent findings indicate that depletion of Pink1 and Prkn promotes pancreatic tumorigenesis in KRAS-driven...
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| Опубликовано в: : | Autophagy |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287677/ https://ncbi.nlm.nih.gov/pubmed/30252570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1526611 |
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