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pH-dependent regulation of SQSTM1/p62 during autophagy

During macroautophagy/autophagy, SQSTM1/p62 plays dual roles as a key mediator of cargo selection and as an autophagic substrate. SQSTM1 links N-degrons and/or ubiquitinated cargoes to the autophagosome by forming homo- or hetero-oligomers, although its N-degron recognition and oligomerization mecha...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Kwon, Do Hoon, Kim, Leehyeon, Song, Hyun Kyu
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287675/
https://ncbi.nlm.nih.gov/pubmed/30290711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1532264
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