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pH-dependent regulation of SQSTM1/p62 during autophagy
During macroautophagy/autophagy, SQSTM1/p62 plays dual roles as a key mediator of cargo selection and as an autophagic substrate. SQSTM1 links N-degrons and/or ubiquitinated cargoes to the autophagosome by forming homo- or hetero-oligomers, although its N-degron recognition and oligomerization mecha...
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| Publié dans: | Autophagy |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287675/ https://ncbi.nlm.nih.gov/pubmed/30290711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1532264 |
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