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CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy

Though CNOT2 is involved in regulation of adipogenic differentiation, apoptotic cell death and metastasis, the underlying autophagic mechanism of CNOT2 was unknown until now. Thus, in the present study, the critical role of CNOT2 in autophagy was elucidated in association with p62/SQSTM1 signaling....

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Foilsithe in:Oncotarget
Main Authors: Jeong, Kwon, Kwon, Hee Young, Jeong, Myoung Seok, Sohn, Eun Jung, Kim, Sung-Hoon
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542246/
https://ncbi.nlm.nih.gov/pubmed/28537904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17682
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