Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development

Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths worldwide, and an association between altered bile acid (BA) metabolism, down‐regulation of farnesoid X receptor (FXR), which is a master regulator of BA metabolism, and hepatocarcinogenesis has been documented. While global FXR defi...

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Bibliografiske detaljer
Udgivet i:Hepatol Commun
Main Authors: Takahashi, Shogo, Tanaka, Naoki, Fukami, Tatsuki, Xie, Cen, Yagai, Tomoki, Kim, Donghwan, Velenosi, Thomas J., Yan, Tingting, Krausz, Kristopher W., Levi, Moshe, Gonzalez, Frank J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287584/
https://ncbi.nlm.nih.gov/pubmed/30556042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1263
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