Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles

INTRODUCTION: Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye. However, it is limited clinically due to its low aqueous solubility and ocular bioavailability. METHODS: In this work,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Shen, Yan, Yu, Yinglan, Chaurasiya, Birendra, Li, Xiaolian, Xu, Ying, Webster, Thomas J, Tu, Jiasheng, Sun, Runing
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287540/
https://ncbi.nlm.nih.gov/pubmed/30584300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S173691
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