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Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles

INTRODUCTION: Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye. However, it is limited clinically due to its low aqueous solubility and ocular bioavailability. METHODS: In this work,...

詳細記述

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書誌詳細
出版年:Int J Nanomedicine
主要な著者: Shen, Yan, Yu, Yinglan, Chaurasiya, Birendra, Li, Xiaolian, Xu, Ying, Webster, Thomas J, Tu, Jiasheng, Sun, Runing
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287540/
https://ncbi.nlm.nih.gov/pubmed/30584300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S173691
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