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Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles

INTRODUCTION: Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye. However, it is limited clinically due to its low aqueous solubility and ocular bioavailability. METHODS: In this work,...

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Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Shen, Yan, Yu, Yinglan, Chaurasiya, Birendra, Li, Xiaolian, Xu, Ying, Webster, Thomas J, Tu, Jiasheng, Sun, Runing
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287540/
https://ncbi.nlm.nih.gov/pubmed/30584300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S173691
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