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Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles

INTRODUCTION: Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye. However, it is limited clinically due to its low aqueous solubility and ocular bioavailability. METHODS: In this work,...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Shen, Yan, Yu, Yinglan, Chaurasiya, Birendra, Li, Xiaolian, Xu, Ying, Webster, Thomas J, Tu, Jiasheng, Sun, Runing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287540/
https://ncbi.nlm.nih.gov/pubmed/30584300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S173691
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