Nrf2 Activation Inhibits Effects of Thrombin in Human Amnion Cells and Thrombin-Induced Preterm Birth in Mice

CONTEXT: Nrf2 is a key transcription factor that modulates cell defense mechanisms against endogenous and exogenous stress. Previously, we reported that thrombin increased matrix metalloproteinases and prostaglandin synthesis in human amnion mesenchymal cells. OBJECTIVE: We sought to determine wheth...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Chigusa, Yoshitsugu, Kishore, Annavarapu Hari, Mogami, Haruta, Word, Ruth Ann
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287450/
https://ncbi.nlm.nih.gov/pubmed/27050800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-1059
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