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Effect of Thrombin on Human Amnion Mesenchymal Cells, Mouse Fetal Membranes, and Preterm Birth

Here, we investigated the effects of thrombin on matrix metalloproteinases (MMPs) and prostaglandin (PG) synthesis in fetal membranes. Thrombin activity was increased in human amnion from preterm deliveries. Treatment of mesenchymal, but not epithelial, cells with thrombin resulted in increased MMP-...

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Detalhes bibliográficos
Main Authors: Mogami, Haruta, Keller, Patrick W., Shi, Haolin, Word, R. Ann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036339/
https://ncbi.nlm.nih.gov/pubmed/24652285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550541
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