Fetal Fibronectin Signaling Induces Matrix Metalloproteases and Cyclooxygenase-2 (COX-2) in Amnion Cells and Preterm Birth in Mice

Fetal fibronectin (fFN) in cervical and vaginal secretions has been used as a predictor of preterm delivery. Here, we clarified the pathological function of fFN on cell type-specific matrix metalloproteinases (MMPs) and prostaglandin synthesis in fetal membranes. Treatment of amnion mesenchymal cell...

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Bibliographic Details
Main Authors: Mogami, Haruta, Kishore, Annavarapu Hari, Shi, Haolin, Keller, Patrick W., Akgul, Yucel, Word, R. Ann
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548503/
https://ncbi.nlm.nih.gov/pubmed/23184961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424366
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