Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer

Fibulin 5 (FBLN5) is an extracellular matrix glycoprotein that suppresses matrix metalloprotease 9 (MMP-9), angiogenesis and epithelial cell motility. Here, we investigated the regulation and function of FBLN5 in epithelial ovarian cancer (EOC). FBLN5 mRNA was down-regulated 5-fold in EOC relative t...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Manders, Dustin B., Kishore, Hari Annavarapu, Gazdar, Adi F., Keller, Patrick W., Tsunezumi, Jun, Yanagisawa, Hiromi, Lea, Jayanthi, Word, Ruth Ann
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865667/
https://ncbi.nlm.nih.gov/pubmed/29581841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24484
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