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Effect of Thrombin on Human Amnion Mesenchymal Cells, Mouse Fetal Membranes, and Preterm Birth

Here, we investigated the effects of thrombin on matrix metalloproteinases (MMPs) and prostaglandin (PG) synthesis in fetal membranes. Thrombin activity was increased in human amnion from preterm deliveries. Treatment of mesenchymal, but not epithelial, cells with thrombin resulted in increased MMP-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mogami, Haruta, Keller, Patrick W., Shi, Haolin, Word, R. Ann
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036339/
https://ncbi.nlm.nih.gov/pubmed/24652285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.550541
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