Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling

Complement activation is involved in the pathogenesis of ischemia reperfusion injury (IRI), which is an inevitable process during kidney transplantation. Therefore, complement-targeted therapeutics hold great potential in protecting the allografts from IRI. We observed universal deposition of C3d an...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hu, Chao, Li, Long, Ding, Peipei, Li, Ling, Ge, Xiaowen, Zheng, Long, Wang, Xuanchuan, Wang, Jina, Zhang, Weitao, Wang, Na, Gu, Hongyu, Zhong, Fan, Xu, Ming, Rong, Ruiming, Zhu, Tongyu, Hu, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2018
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287101/
https://ncbi.nlm.nih.gov/pubmed/30429287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800987
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