TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity‐induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice

Inflammation contributes to obesity‐related hyperinsulinemia and insulin resistance, which often precede type 2 diabetes. Inflammation is one way that obesity can promote insulin resistance. It is not clear if the extent of obesity, hyperinsulinemia, or hyperglycemia, underpins changes in cellular i...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Breznik, Jessica A., Naidoo, Avee, Foley, Kevin P., Schulz, Christian, Lau, Trevor C., Loukov, Dessi, Sloboda, Deborah M., Bowdish, Dawn M. E., Schertzer, Jonathan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286899/
https://ncbi.nlm.nih.gov/pubmed/30548217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13937
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