Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

Levels of inflammatory mediators in circulation are known to increase with age, but the underlying cause of this age-associated inflammation is debated. We find that, when maintained under germ-free conditions, mice do not display an age-related increase in circulating pro-inflammatory cytokine leve...

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Bibliografiska uppgifter
I publikationen:Cell Host Microbe
Huvudupphovsmän: Thevaranjan, Netusha, Puchta, Alicja, Schulz, Christian, Naidoo, Avee, Szamosi, J.C., Verschoor, Chris P., Loukov, Dessi, Schenck, Louis P., Jury, Jennifer, Foley, Kevin P., Schertzer, Jonathan D., Larché, Maggie J., Davidson, Donald J., Verdú, Elena F., Surette, Michael G., Bowdish, Dawn M.E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392495/
https://ncbi.nlm.nih.gov/pubmed/28407483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.03.002
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