Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

Levels of inflammatory mediators in circulation are known to increase with age, but the underlying cause of this age-associated inflammation is debated. We find that, when maintained under germ-free conditions, mice do not display an age-related increase in circulating pro-inflammatory cytokine leve...

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Pubblicato in:Cell Host Microbe
Autori principali: Thevaranjan, Netusha, Puchta, Alicja, Schulz, Christian, Naidoo, Avee, Szamosi, J.C., Verschoor, Chris P., Loukov, Dessi, Schenck, Louis P., Jury, Jennifer, Foley, Kevin P., Schertzer, Jonathan D., Larché, Maggie J., Davidson, Donald J., Verdú, Elena F., Surette, Michael G., Bowdish, Dawn M.E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392495/
https://ncbi.nlm.nih.gov/pubmed/28407483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.03.002
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